Deciphering mRNA Sequence Determinants of Protein Production Rate
نویسندگان
چکیده
منابع مشابه
Deciphering mRNA Sequence Determinants of Protein Production Rate
One of the greatest challenges in biophysical models of translation is to identify coding sequences features that affect the rate of translation and therefore the overall protein production in the cell. We propose an analytic method to solve a translation model based on the inhomogeneous totally asymmetric simple exclusion process, which allow us to unveil simple design principles of nucleotide...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2018
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.120.128101